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Tuesday, September 16, 2008

Tobacco Virus can be a Medicine

As a general tobacco can cause bad effect to out body, people just said about bad effect of this material. Scientist have found different about this material, because tobacco is a natural plant that available for use by human being, but not just for be sucked. The tobacco virus can be a medicine.

This knowledge is involving a molecular grade technology, on tobacco sometime live a virus that can broken their growth. Scientists are using a modified tobacco virus to deliver delicate gene therapies into the heart of diseased cells, with the potential to treat most cancers, viruses and genetic disorders.

The tobacco mosaic virus, which plagues the plant but is harmless to humans, is hollowed out and filled with "small interfering RNA" molecules, or siRNA, which some scientists consider to be the most significant development in medicine since the discovery of vaccines.

Bentley's team has successfully hollowed out the virus and filled it with siRNA, and then used it to slip the frail substance into all sorts of cells, from kidney tissue to cancer. The researchers have proven that the tiny capsules provide adequate protection, and that they release their payloads once inside -- hitting their target genes right on the mark.

The short, double-stranded RNA molecules known as siRNA can program cells to destroy disease-causing proteins. Their molecules turn on a cell's own built-in disease-fighting mechanisms. They can be programmed for a wide range of ailments -- from cancers to viruses -- and because they use the cell's own defense mechanisms, they produce minimal side effects.

In addition to treating cancers and genetic disorders, siRNA could prove useful against a variety of rare diseases that have, and always will be, overlooked by big pharmaceutical companies -- the long tail of disease.

Is those experiment going smoothly? No the problem is not easy to overcome, problem is in the delivery: siRNA molecules are very fragile, and can’t get where they need to go without some assistance. So this technology still need more long time in order able applied as medicine for rare diseases like cancer, virus infection diseases and others.

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